The Berkshire Overdose and Addiction Prevention Collaborative (BOAPC) collectively implements local policy, practice, systems, and/or environmental changes to reduce harms from opioid and stimulant use, and to prevent substance-related deaths and harmful impacts throughout the 32 municipalities in Berkshire County. The county-wide collaborative includes community service organizations, medical and behavioral health practitioners, local government, law enforcement, housing agencies, workforce development, harm reduction, treatment/recovery providers, education, people in recovery, and individual citizens alike. BOAPC provides an engaging space for these partners to work together to identify needs in the community and implement solutions.